Research & Innovation

Faculty Research

2b1b761e-fa19-4ddb-92e7-dc9eab669307Name: Antonio (Tony) Amelio
Departments: Dental Ecology/Dental Research; Lineberger Comprehensive Cancer Center; Biomedical Research Imaging Center
Title: Assistant Professor
Telephone: (919) 537-3309 office, (919) 537-3405 lab
Mailing Address:
UNC School of Dentistry
385 South Columbia Street CB #7455
Chapel Hill, NC 27599-7455
Office: 3510 Koury Oral Health Sciences Bldg.
Lab: 3605 Koury Oral Health Sciences Bldg.
Email: antonio_amelio@unc.edu
Lab URL: http://ameliolab.web.unc.edu/ (under construction)
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Antonio+L+Amelio&u_id=1980109125
Description of Research:
The Amelio Lab applies an interdisciplinary approach to understand the mechanisms underlying the development of oral, head, and neck cancers. To this end, we are investigating the signaling pathways that drive mucoepidermoid carcinoma of the salivary gland and oral squamous cell carcinoma using a combination of bioinformatics, animal models, and molecular genetic analyses.
Keywords:
Biochemistry, Carcinogenesis, Cell biology, Cell culture, Gene expression, Genetics, Molecular biology, Neoplasia, Oral biology, Salivary glands, Signal Transduction, Biomarkers, Bioinformatics
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, postdoc

 


 

arnoldName: Roland Arnold
Department: Diagnostic Sciences/Dental Research
Title: Professor
Telephone: (919) 537-3165
Mailing Address:
UNC School of Dentistry
CB #7457
Chapel Hill, NC 27599-7457
Office: 3043 First Dental Building
Lab: 3030 First Dental
Email: roland_arnold@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Roland+R+Arnold&u_id=500 1571
Description of Research:
Our interests include host-pathogen interactions at mucosal surfaces including the oral cavity and the respiratory and gastrointestinal tracts. Our studies examine both innate and acquired soluble host defense factors that are delivered to mucosal surfaces by exocrine secretions. We are also interested in the strategies of both pathogens and indigenous (normal flora) microbes for evading these host defense factors. As professional phagocytic cells such as the polymorphonuclear neutrophilic leukocytes employ similar antimicrobial agents to that found in secretions, we are interested in how these function in the cell. In order to understand the importance of these functions, we are interested in patient populations that have selective dysfunctions in discrete components of either exocrine secretions (e.g. IgA deficiency, cystic fibrosis, Sjogrens, ionic cofactors) or in neutrophils (e.g. chronic   granulomatous disease, specific granule deficiency, lactoferrin, defensins, myeloperoxidase, adhesins, elastase). We are interested in specific pathogens associated with periodontal diseases, caries, chronic inflammatory diseases, respiratory pathogens including cystic fibrosis, COPD, lung transplants. These pathogens include among others Streptococcus mutans, Lactobacillus acidophilus, Porphyromonas gingivalis, Fusobacterium nucleatum, Prevotella intermedia, Tannerella forsythia, Aggregatibacter actinomycetemcomitans, Pseudomonas aeruginosa and Burkholderia cepacia. We also have expertise in the evaluation of efficacies of antimicrobials to a variety of target microorganisms.
Keywords:
Antimicrobial agents/inhibitors, Biofilm, Caries organisms, Cell biology, Host- microbial interactions, Infection, Inflammation, Mucosal diseases, Periodontal organisms, Saliva, mucosal immunity, secretory immunity, ecology, innate immunity
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

baderName: Jim Bader
Department: Operative Dentistry
Title: Research Professor
Telephone: (919) 537-3979
Office: 446 Brauer Hall
Address:
UNC School of Dentistry
Operative Dentistry CB #7450
Chapel Hill, NC 27599-7450
Email: jim_bader@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=James+D+Bader&u_id=5001514&oe_id=1&o_id=55
Description of Research:
Dental health services research
Keywords: Delivery systems; Quality; Effectiveness; Outcome (Health); Epidemiology;
Willingness and interest to advise/mentor:
Graduate student, postdoc and/or junior faculty member, but must be long distance, not based in Chapel Hill

 


 

bencharitName: Sompop Bencharit
Department: Prosthodontics
Title: Assistant Professor
Telephone: (919) 537-3961
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 342 Brauer Hall
Lab: 3rd. floor Koury Oral Health Science Bldg.
Email: sompop_bencharit@unc.edu
Lab URL: http://www.unc.edu/~benchars
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Sompop+Bench arit&u_id=5000746
Description of Research:
Dr. Bencharit is a protein structural biologist specializing in protein X- ray crystallography. He has his research interests in structural biology and its application to human diseases in particular the role of signaling proteins involved in vessel development. In addition he is also interested in the clinical application of salivary proteomics using an advanced mass spectrometry proteomics and systems biology. His   main laboratory goals include (1) structural and functional studies of cerebral cavernous malformation (CCM), a genetic disorder resulting in vascular defects in the brain causing hemorrhagic stroke; (2) salivary proteomic analysis and biomarker discovery; and (3) enhancing tissue healing and osseointegration of dental implants.
Keywords: Salivary proteomics, Dental implants, Tissue regeneration, Cerebral Cavernous Malformation
Willingness and interest to advise/mentor:
Undergraduate/college student, graduate student, MD or DDS or PhD students, and junior faculty member

 


 

cooperName: Lyndon Cooper
Department: Prosthodontics
Title: Distinguished Professor
Telephone: (919) 537-3175
Mailing Address:
UNC School of Dentistry
Prosthodontics
385 S. Columbia St CB #7450
Chapel Hill, NC 27599-7450
Office: 4610 Koury Oral Health Sciences Building
Lab: 4617D Koury Oral Health Sciences Building
Email: lyndon_cooper@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Lyndon+F+Coo per&u_id=5001150
Keywords: Bone biology, dental implants
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

divarisName: Kimon Divaris
Department: Pediatric Dentistry
Title: Associate Professor
Telephone: (919) 537-3556
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 234 Brauer Hall
Lab: 4th floor Koury Oral Health Sciences Bldg.
Email: kimon_divaris@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Kimon+Divaris&u_id=1980030310
Keywords: Behavioral science, Caries, Education research, Epidemiology, Fluoride, Genetics, Periodontal disease, Periodontal organisms, Quality of life, Stress, Health services research, health literacy; pediatric dentistry, health services research; health literacy; pediatric dentistry
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, postdoc.

 


 

duqumName: Ibrahim Duqum
Department: Prosthodontics
Title: Clinical Assistant Professor
Telephone: (919) 537-3964
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 337 Brauer Hall
Email: duqumibr@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Ibrahim+S+Duqum&u_id=5002531
Description of Research:
All Ceramic restorations. Digital Dentistry in both restorative and implant dentistry. CAD/CAM in dentistry. Osseointegration and survival and success of dental implants. Edentulism and attachments for complete dentures. Survival and success of dental extracoronal restorations. Dental educational research and application of digital dentistry in dental education
Keywords: CAD/CAM, Ceramics, Clinical trials, Dental materials, Education research, Esthetics, Implants, Impression materials, Prostheses, Technology
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student  and junior faculty member

 


 

essickName: Greg Essick
Department: Prosthodontics
Title: Professor
Telephone: (919) 537-3287
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 5417H Koury Oral Health Sciences
Lab: 5417H Koury Oral Health Sciences
Email: essickg@unc.edu
Lab URL: http://www.dentistry.unc.edu/ce/ahec/biosketch.cfm?employeeid=1947
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Gregory+K+Ess ick&u_id=5000185
Description of Research:
Normal orofacial sensation, alterations in orofacial sensation after trigeminal nerve injury, mechanisms underlying chronic pain, the association between poor sleep and chronic pain, obstructive sleep apnea, novel therapies to treat obstructive sleep apnea
Keywords: Assessment, Central nervous system/peripheral nervous system, Clinical trials, Human, Pain, Physiology, Nerve injury; sleep apnea
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

Eric T. Everett, PhDName: Eric T. Everett
Department: Pediatric Dentistry
Title: Professor & Associate Dean for Research
Telephone: (919) 537-3182
Mailing Address:
UNC School of Dentistry
Dental Research CB #7455
Chapel Hill, NC 27599-7455
Office:
5501H Koury Oral Health Sciences
Lab: 4417 Koury Oral Health Sciences
Email: eric_everett@unc.edu
Lab URL: http://genomics.unc.edu/faculty/webpages/everett.html
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Eric+T+Everett&uid=5002498
Description of Research:
Genetic basis for acquired and congenital defect of the oral/craniofacial/dental complex
Keywords: Ameloblasts, Anatomy, Animal Models, Biochemistry, Bone, Cell biology, Enamel, Fluorosis, Gene expression, Genetics
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

foxName: Lynn Fox
Department: Dental Ecology
Title: Assistant Clinical Professor
Telephone: (919) 537-3509
Mailing Address:
UNC School of Dentistry
Craniofacial Center CB #7450
Chapel Hill, NC 27599-7450
Office: 008 Brauer Hall
Email: lynn_fox@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Lynn+M+Fox& u_id=5002511
Description of Research:
Craniofacial team functioning, healthcare literacy, speech and language, stuttering
Keywords: Cleft lip-palate, Speech-Language Pathology, Stuttering
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

frazierName: Sylvia Frazier-Bowers
Department: Orthodontics
Title: Associate Professor
Telephone: (919) 966-2762
Mailing Address:
UNC School of Dentistry
Orthodontics CB #7450
Chapel Hill, NC 27599-7450
Office: 271 Brauer Hall
Lab: 4417D Koury Oral Health Sciences
Email: sylvia_frazier@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Sylvia+A+Frazi er%2Dbowers&uid=5000996
Description of Research:
My research interests include understanding the genetic basis of craniofacial anomalies relevant to the field of orthodontics. Specifically, I investigate the genetic basis of dentofacial variation in the skeletal Class III dentofacial phenotype (1-5% prevalence); tooth agenesis (congenitally missing teeth) and primary failure of eruption (PFE). My current efforts focus on gene discovery and phenotype dissection of dentofacial variation using 1) 2 /3 dimensional methods for rigorous clinical characterization, 2) genotyping and linkage analysis and 3) mutational analysis using the candidate gene approach. This translational research program has grown over the past six years and inspires a paradigm shift in orthodontics from “how to move teeth to how teeth move.”  My recent genetic studies in PFE represent the quintessential translational research product; knowledge of a PTH1R mutation a priori prevents the futile attempt at early orthodontic interventions saving the practioner and patient time and money.
Keywords: Bone, Cephalometric analysis, Diagnosis, Genetics, Malocclusion, Orthodontics, Osteoblasts/osteoclasts
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

khanName: Asma Khan
Department: Endodontics
Title: Associate Professor
Telephone: (919) 537-3389
Mailing Address:
UNC School of Dentistry
Chapel Hill, NC 27599-7454
Office: 1170 First Dental Building
Lab: 5617C  Koury Oral Health Sciences Bldg.
Email: asma_khan@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Asma+Ahmed+Khan&u_id=5002849
Description of Research:
Pain mechanisms and management. Role of microRNA in inflammation and pain. Regenerative Endodontics; Development of new diagnostics
Willingness and interest to mentor:
Undergraduate, DDS and Grad students

 


 

koName: Ching-Chang Ko
Department: Orthodontics
Title: Professor
Telephone: (919) 537-3763
Mailing Address:
UNC School of Dentistry
275 Brauer Hall CB #7450
Chapel Hill, NC 27599-7450
Office: 269 Brauer Hall
Lab: 3617 Koury Bldg
Email: ching-chang_ko@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Ching-Chang+Ko&u_id=5002668&oe_id=1&o_id=21
Description of Research:
Biomechanics/biomaterials related bone remodeling and regeneration, dopamine-associated bone remodeling, synthesis of polydopamine bioinspired bone substitute, orthodontic biomechanics, orthodontic biomaterials, finite element analysis of dental biomechanics
Keywords: Bone, Orthodontics, Biomechanics, Biomaterials, Neural-osseous biology, Bone Tissue Engineering
Willingness and interest to mentor:
Undergraduate/college  student, graduate  student, undergraduate DDS  student, postdoc and/or junior faculty member

 


 

Lorne Koroluk, DMD, MSD, MSName: Lorne D. Koroluk
Department: Orthodontics
Title: Associate Professor and Chair
Telephone: (919) 537-3784
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 237 Brauer Hall
Email: lorne_koroluk@unc.edu
Keywords: Malocclusion, growth and development, teaching, ulcerations; fungal; cancer; facial; dermatologic
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, postdoc and/or junior faculty member

 


 

kutcherName: Mark Kutcher
Department: Dental Ecology
Title: Associate Professor
Telephone: (919) 537-3140
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 5405C Koury Oral Health Sciences
Email: kutcherm@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Mark+J+Kutcher&u_id=5001266
Description of Research:
Diagnosis and management of oral diseases such as viral, fungal, ulcerations etc.; facial cancer; dental management of medically compromised patients;
Keywords: Antimicrobials, Clinical trials, Halitosis, Mucosal diseases, Neoplasia, Oral mucosa, Pathology, Teaching, Viruses, ulcerations; fungal; cancer; facial; dermatologic
Willingness and interest to mentor:
Graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

LampirisName: Lewis N. Lampiris
Department: Dental Ecology
Title: Clinical Associate Professor
Telephone: (919) 537-3580
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 467 Brauer Hall
Email: leweis_lampiris@unc.edu
Description of Research:
Health Services , Health Disparities
Keywords: Access to Care, Health Policies, Public Health Dentistry
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student

 


 

Jessica Y. Lee, DDS, MPH, PhDName: Jessica Lee
Department: Pediatric Dentistry
Title: Chair, Distinguished Professor
Telephone: (919) 537-3271
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 228 Brauer Hall
Lab: 4501 Koury Oral Health Sciences Bldg.
Email: leej@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Jessica+Y+Lee&u_id=5000598
Description of Research:
Health Services Research, Epidemiology, Health Disparities, Healthy Literacy
Keywords: Access to Care, Behavioral science, Delivery systems, Health Policies research, Public Health Dentistry
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

maurielloName: Sally Mauriello
Department: Dental Ecology
Title: Professor
Telephone: (919) 537-3474
Mailing Address:
UNC School of Dentistry
CB #7455
Chapel Hill, NC 27599-7455
Office: 5504 Koury Oral Health Science Bldg.
Email: sally_mauriello@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Sally+M+Mauriello&u_id=5000529
Description of Research:
My research interests are in the areas of: dental radiology, geriatric dentistry, examiner calibration, root caries, dental hygiene.
Keywords: Access to Care, Aging, Cardiovascular disease, Caries, Clinical trials, Elderly, Gerontology, Gingivitis, Periodontal disease, Preventive dentistry, Clinical examiner calibration, Clinical examiner calibration
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

2014-11-05_MiguezName: Patricia (Pat) Miguez
Department: Operative Dentistry/Dental Research
Title: Clinical Assistant Professor
Telephone: (919) 537-3324
Mailing Address:
UNC School of Dentistry
CB #7455
Chapel Hill, NC 27599-7455
Office: 4606 Koury Oral Health Sciences Building
Lab: 4605-4611 Koury Oral Health Sciences Building
Email: patricia_miguez@unc.edu
Lab URL: http://patmiguez.web.unc.edu
Description of Research:
Currently there is a gap of knowledge in that we have not been able to identify a reliable form of preventing dentin and bone loss in various physiological and pathological scenarios. My long-term goals are to unveil novel mechanisms of protecting such mineralized tissues, characterize new effective agents and ultimately bring these agents to clinical practice. My research studies have concentrated in understanding collagen biochemistry and tissue mechanical properties link; promotion of mineralization (re-mineralization) in dentin and bone and, more recently, focused in the role of the proteoglycan biglycan in promotion of craniofacial bone regeneration through modulation of bone morphogenetic protein function. Other biological and translational experiments are in development to promote dentin formation. Another area of interest is on integrative medicine where I seek to understand how natural compounds (phytochemicals) act on cell behavior, extracellular matrix quality and mineralization as well as their effect on oral diseases development such as caries and periodontal disease.
Keywords: Animal, collagen, regeneration, biomaterials, bone, dentin, extracellular matrix molecules, mineralization, tissue engineering, osteoblasts/osteoclasts, phytochemicals, signal transduction, molecular biology, mechanical properties, proteoglycans, tissue and organ culture
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student and postdoc

 


 

milanoName: Michael Milano
Department: Pediatric Dentistry
Title: Clinical Associate Professor
Telephone: (919) 537-3782
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 228 Brauer Hall
Email: milanom@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Michael+Milano&u_id=5002559
Description of Research:
The dental needs of children with special health care needs. The use of sedation in children in order to provide dental care.
Keywords: Access to Care, Anxiety, Behavioral science, Children, Cleft lip-palate, Education research, Infants
Willingness and interest to mentor:
Graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

morettiName: Antonio J. Moretti
Department: Periodontology
Title: Clinical Associate Professor
Telephone: (919) 537-3734
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 120 Brauer Hall
Email: antonio_moretti@unc.edu
Description of Research:
Clinical Research
Willingness and interest to mentor:
Undergraduate/College student, graduate student, undergraduate DDS or DH student and/or junior faculty member

 


 

nackleyName: Andrea G. Nackley
Departments: Endodontics, Pharmacology, Curriculum in Neurobiology
Title: Associate Professor
Telephone: (919) 537-3204
Mailing Address:
Center for Pain Research and Innovation
University of North Carolina
385 South Columbia Street
Chapel Hill, NC 27599-7455
Office: Room 5506 Koury Oral Health Sciences Building
Email: andrea_nackley@unc.edu
Lab URL: http://nackleylab.web.unc.edu/
Description of Research:
My lab integrates molecular genetics, animal models, and clinical epidemiologic measures to better understand the neurobiological processes underlying chronic pain. My research objectives are to 1) identify and characterize signaling processes that drive persistent pain conditions, 2) evaluate the potential functionality of common genetic polymorphisms that interact with environmental events to produce persistent pain conditions, and 3) identify biological markers predictive for the development of persistent pain conditions, including the severity and duration of the disorder as well as optimal management strategies for different individuals.
Willingness and interest to advise/mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

tungName: Tung Nguyen
Department: Orthodontics
Title: Assistant Professor
Telephone: (919) 537-3764
Mailing Address:
UNC School of Dentistry
Orthodontics CB #7450
Chapel Hill, NC 27599-7450
Office: 264 Brauer Hall
Lab: Old Dental 2080
Email: nguyentu@unc.edu
Lab URL: https://www.dentistry.unc.edu/research/orofacial_imaging_lab/
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Tung+T+Nguyen&u_id=5002535
Description of Research:
My research interests include growth modification of Class III malocclusions using skeletal anchorage. The ultimate goal of my research is to develop and refine a protocol that will help reduce the need for orthognathic surgery in this population of patients. We recently expanded our protocol to include craniofacial cleft and syndromic patients and started a multi-center study. My lab is involved in the development of 3-D imaging software and methodology to help assess growth and treatment changes. Lastly, I’m interested in CAD/CAM and digital technology to increase the effectiveness and efficiency of orthodontic treatment.
Keywords: Adolescence, CAD/CAM, Cephalometric analysis, Cleft lip-palate, Digital image analysis, Growth & development, Orthodontics, Technology
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

2013-08-16_StevenOffenbacherName: Steven Offenbacher
Department: Periodontology
Titles: WR Kenan Distinguished Professor and Chair of Periodontology, Director, Center for Oral and Systemic Diseases
Telephone: (919) 537-3205
Mailing Address:
UNC School of Dentistry
385 S. Columbia St CB #7450
Chapel Hill, NC 27599-7450
Office: 3501F Koury Oral Health Science Bldg.
Lab: 3417 Koury Oral Health Science Bldg.
Email: steve_offenbacher@unc.edu
Lab URL: https://www.dentistry.unc.edu/research/corefacilities/cytokine.cfm
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Steven+Offenbacher&u_id=5001097&oe_id=1&o_id=61
Description of Research:
I have been a clinical scientist engaged in translational research investigating periodontal disease and the role of oral infection in systemic disease for 30 years. Our laboratory program emphasizes host-pathogen interaction and the regulation of inflammation as an effector mechanism that mediates not only periodontal destruction, but systemic sequelae of oral infection. More recently we have focused on the whole transcriptome changes associated with periodontal disease and the role of epigenetics in this process. In addition we have published GWAS of periodontal phenotypes using our Dental ARIC population. Clinical translational research has been the fundamental focus of my career. I currently have 15 active, funded clinical research protocols and have a total of 41 completed protocols during my time here at UNC which include Phase 1-4 FDA investigations and population- based studies. We have broad experience with murine models of oral infection.
My interests focus on biofilm infections and inflammation at mucosal surfaces. This has been the fundamental research component to my translational research interests and the focus point of my mentoring.  I have trained PhD, Masters and Translational Research students in Dentistry, the School of Public Health and Medicine.
Keywords: Periodontal disease, oral immunology, oral-systemic disease, pregnancy complications, cardiovascular disease
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

BeatrizPaniagua

Name: Beatriz Paniagua
Departments: Psychiatry (main appointment), Orthodontics, Computer Science (adjunct)
Title: Assistant Professor
Telephone: (919) 843-9497
Mailing Address:
Medical School Wing C
Third floor, Suite 356, CB 7160
Chapel Hill, NC 27599-7160
Office: Medical School Wing C, Suite 356
Lab: 2080 Old Dental (Ortho) 355 Medical School Wing C (Psychiatry)
Email: beatriz_paniagua@med.unc.edu or beatriz_paniagua@unc.edu
Lab URL: http://www.med.unc.edu/psych/research/niral and https://www.dentistry.unc.edu/research/orofacial_imaging_lab/
ReachNC Link:
http://www.experts.scival.com/ReachNC/expert.asp?n=Beatriz+Paniagua&u_id=1980033241
Description of Research:
I have always been interested in how computational sciences can be used to address biological questions. My research background is in statistical shape analysis applied to brain morphometry and cranio facial morphology, deformable registration applied to shape, image processing, free-open source software development for the biological and medical sciences.
Keywords: Shape analysis, brain morphometry, craniofacial morphology, image processing, software development
Willingness and interest to advise/mentor:
Graduate student (MS and PhD) interested in computer-based orofacial imaging research

 


 

ParkName: Jongbae Jay Park
Departments: Endodontics, Center for Pain Research and Innovation
Title: Clinical Assistant Professor
Telephone: (919) 537-3286
Mailing Address:
385 South Columbia St.
Center for Pain Research and Innovation
UNC School of Dentistry
Koury Oral Health Sciences Building 5417P, CB#7455
Chapel Hill, NC 27599-7455
Office: Koury Oral Health Sciences Building 5417P
Email: jongbae_park@med.unc.edu
Lab URL: http://www.med.unc.edu/phyrehab/faculty/jongbae-jay-park-kmd- phd
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Jongbae+Jay+P ark&u_id=5002737
Description of Research:
Acupuncture is proven to clinically improve TMD related pain. The mechanism by which acupuncture improves TMD related pain, however, is largely unknown. My research aims at findings any correlation between clinical outcomes and the profiles of cytokines and growth factors in TMD following acupuncture, and elucidating the role of circulating cytokines and growth factors in mediating the putative analgesic effects of acupuncture. My translational research involves observational study, clinical trial, and literature study method.
Keywords: Mechanism of acupuncture, Temporomandibular Disorders, Orofacial pain, Chronic pain, Integrative medicine, Asian Medicine, Clinical research method, blinding
Willingness and interest to advise/mentor:
Undergraduate/college student, graduate student

 


 

pattonName: Lauren Patton
Department: Dental Ecology
Title: Professor
Telephone: (919) 966-2787
Mailing Address:
UNC School of Dentistry
Dental Ecology CB #7450
Chapel Hill, NC 27599-7450
Office: 467A Brauer Hall
Email: lauren_patton@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Lauren+L+Patton&u_id=5000394
Description of Research:
Clinical trials for mucosal disease treatment or prevention/Oral cancer prevention and early diagnosis/Management of patients with systemic disease/Oral and systemic disease interaction/HIV infection and AIDS patient dental care, access to care, oral lesions/Health services research, outcomes research, and public health dentistry topics/Systematic reviews to assess evidence base for dental treatment processes
Keywords: Clinical trials, Diagnosis, Epidemiology, HIV infection, Health Policies research, Mucosal diseases, Public Health Dentistry, Salivary dysfunction, Systematic review, Tobacco, Oral cancer/Medically complex patients, Oral cancer/Medically complex patients
Willingness and interest to mentor:
graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

phillipsName: Ceib Phillips
Department: Orthodontics
Title: Professor
Telephone: (919) 537-3373
Mailing Address:
UNC School of Dentistry
Orthodontics CB #7450
Chapel Hill, NC 27599-7450
Office: 3120 Old Dental
Lab(s): 2090 and 2080 Old Dental
Email: ceib_phillips@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Ceib+L+Phillips&u_id=5000306
Description of Research:
Clinical Trial Methodology/Preparation for and Recovery from Surgery–Patient Centered Outcomes/Access to Care–Patient/Caregiver Centered
Keywords: Access to Care, Assessment, Cleft lip-palate, Clinical trials, Effectiveness, Methodology, Orthodontics, Outcome (Health), Quality of life, Surgery
Willingness and interest to mentor:
Graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

pimentaName: Luiz Pimenta
Department: Dental Ecology
Title: Clinical Professor
Telephone: (919) 537-3691
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 001 Brauer Hall
Email: pimental@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Luis+Andre+F+Pimenta&u_id=5002643
Description of Research:
Clinical research in cleft lip/palate and craniofacial anomalies. / Also, clinical and lab research in cariology
Keywords: Assessment, Biofilm, Bone repair, Caries, Cariology, Cleft lip-palate, Clinical Trials, Esthetics, Fluoride, Prostheses
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

quinonezName: Rocio B Quinonez
Department: Pediatric Dentistry
Title: Associate Professor
Telephone: (919) 537- 3955
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 238 Tarrson Hall
Lab: 1038 Tarrson Hall
Email: uino_quinonez@unc.edu
Description of Research:
Prenatal and early childhood oral health; Interface between medicine and dentistry, Interprofessional education, Access to care.
Keywords: Prenatal, infant oral health, Interprofessional education, Clinical trials
Willingness and interest to mentor:
Graduate student, undergraduate DDS or DH student, or junior faculty member

 


 

ritterName: Andre Ritter
Department: Operative Dentistry
Title: Professor
Telephone: (919) 843-6356
Mailing Address:
UNC School of Dentistry
Operative Dentistry CB #7450
Chapel Hill, NC 27599-7450
Office: 441 Brauer Hall
Email: rittera@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Andre+Ritter&u_id=5000547
Description of Research:
Caries risk assessment and management / Dental materials and adhesion / Esthetic Dentistry
Keywords: Adhesion, Biomaterials, Caries, Composites, Esthetics
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

robertsName: Michael Roberts
Department: Pediatric Dentistry
Title: Clinical Professor
Telephone: (919) 537-3781
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 230 Brauer Hall
Email: mike_roberts@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Michael+W+Roberts&u_id=5001584
Description of Research:
Oral implications of eating disorders. Basal metabolism index (BMI) percentile and caries incidence. Dental implications associated with medically compromised children.
Keywords: Access to Care, Caries, Eating disorders,  Basal metabolism index (BMI)
Willingness and interest to mentor:
Graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

sandersName: Anne Sanders
Department: Dental Ecology
Title: Assistant Professor
Telephone: (919) 537-3275
Mailing Address:
UNC School of Dentistry
Dental Ecology CB #7450
Chapel Hill, NC 27599-7450
Office: 4502 Koury Oral Health Sciences
Email: anne_sanders@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Anne+Elizabeth+Sanders&u_id=5002908
Description of Research:
Oral epidemiology, social epidemiology, sleep-disordered breathing, pain; periodontal disease, NHANES
Keywords: Population, causality, survey methods, analytic methods
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

sladeName: Gary Slade
Department: Dental Ecology
Title: Professor
Telephone: (919) 537-3273
Mailing Address:
UNC School of Dentistry
Dental Ecology CB #7450
Chapel Hill, NC 27599-7450
Office: 4501E Koury Oral Health Sciences
Email: gary_slade@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Gary+D+Slade
&u_id=5001357
Description of Research:
Oral epidemiology; Orofacial pain; Oral health related quality of life; Population prevention of oral disease
Keywords: Epidemiology, Pain, Public Health Dentistry, Quality of life
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

steinName: Margot Stein
Department: Dental Ecology
Title: Clinical Associate Professor
Telephone: (919) 537-3510
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 006 Brauer Hall
Email: steinm@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Margot+B+Stei n&u_id=5000885
Description of Research:
1038. Social and emotional adjustment of children and adolescents/2. Quality of life for children and adolescences with craniofacial anomalies/ 3. Learning and developmental disabilities in childhood and adolescence/ 4. Graduate training in ethics and professionalism/ 5. Motivational Interviewing in the health professions/ 6. Access to health care
Keywords: Access to Care, Anxiety, Assessment, Behavioral science, Children, Cleft lip-palate, Learning, Psychology, Quality of life, Teaching, Ethics, professionalism, Ethics, professionalism
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

tawilName: Peter Z Tawil
Department: Endodontics
Title: Interim Graduate Program Director / Assistant Professor
Telephone: (919) 537-3376
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 1150 First Dental Bldg.
Email: peter_tawil@unc.edu
Description of Research:
Endodontic and Endodontic Surgery
Keywords: Periapical Microsurgery, Dental Defects, Endodontic Instruments, Endodontic Materials, Outcome, Pulpotomies
Willingness and interest to mentor:
Graduate student, postdoc and/or junior faculty member

 


 

tchivilevaName: Inna Tchivileva
Department: Endodontics Dental Research
Title: Research Assistant Professor
Telephone: (919) 537-3291
Mailing Address:
UNC School of Dentistry
CB #7455
Chapel Hill, NC 27599-7455
Office: 5417J Koury Oral Health Sciences
Lab: 1038 Tarrson Hall
Email: chivilei@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Inna+Tchivilev a&u_id=710758721
Description of Research:
My research objectives are to identify genetic variants influencing pain sensitivity, the likelihood of developing chronic pain diseases, and the response to pain therapy. I am interested in developing and conducting pharmacogenetic clinical trials translating basic research findings into clinical practice. Recently, my efforts have concentrated on studying the effect of catecholamine-O-methyltransferase gene polymorphism on response to beta-adrenergic blocker therapy in patients with temporomandibular joint disorder.
Keywords: Central nervous system/peripheral nervous system, Gene expression, Genetics, Human, Magnetic Resonance Imaging, Neuroscience, Outcome (Health), Pain, Pharmacology, Psychology Clinical Trials, Clinical trials
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student

 


 

walterName: Rick Walter
Department: Operative Dentistry
Title: Clinical Associate Professor
Telephone: (919) 537-3596
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 445 Brauer Hall
Lab: 4611 Koury Bldg
Email: walterr@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Ricardo+Walter&u_id=1980109132&oe_id=1&o_id=56
Description of Research:
Development and in vitro and clinical testing of resin-based materials used in restorative dentistry
Keywords: Clinical trials, composites, dental materials, dentin, dentin bonding agents, erosion
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

WhiteRName: Raymond (Ray) White
Department: Oral & Maxillofacial Surgery
Title: Professor
Telephone: (919) 537-3944
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 149 Brauer Hall
Email: ray_white@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Raymond+P+W hite&u_id=5001313
Description of Research:
Clinical research topics related to orthognathic surgery, 3rd molar management
Keywords: Biofilm, Clinical trials, Periodontal disease, Quality of life, Surgery
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

wrightName: John Timothy Wright
Department: Pediatric Dentistry
Titles: Endodontics Interim Chair, Bawden Distinguished Professor
Telephone: (919) 966-2739
Mailing Address:
UNC School of Dentistry
Pediatric Dentistry CB #7450
Chapel Hill, NC 27599-7450
Office: 1617F Koury Oral Health Sciences Bldg.
Lab: 4110 Koury Oral Health Sciences
Email: tim_wright@unc.edu
Lab URL:
https://www.dentistry.unc.edu/secure/resources/directories/detail.cf m?employeeid=1975
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=John+T+Wrigh t&u_id=5001648
Description of Research:
My research interests involve advancing our understanding of the fundamental molecular mechanisms involved in tooth and craniofacial formation and the use of this information in advancing our diagnostic and clinical treatments of hereditary craniofacial defects. My laboratory is also investigating the molecular controls involved in initiating, defining and maintaining odontogenic tumors in humans.
These projects are being completed using a variety of human and animal models including the study of human hereditary conditions and transgenic mice. Recent work has been initiated to investigate the human oral microbiome and its metabolomics and related to dental caries to identify their potential utility in risk assessment.
Keywords: Ameloblasts, Animal, Models, Cariology, Dentin, Diagnosis, Enamel, Fluoride, Genetics, Human
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

wrightRName: Robert F. Wright
Department: Prosthodontics
Title: Professor and Chair
Telephone: (919) 537-3435
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: Brauer 335
Email: robert_wright@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Robert+F+Wrig ht&u_id=1980033419&oe_id=1&o_id=22
Description of Research:
Implants, materials, mentoring, educational, clinical trials, maxillofacial prosthetics, stereo lithography, taper and biomechanical principles of crown preparations, and digital dentures research.
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS

 


 

yamauchiName: Mitsuo Yamauchi
Department: Periodontology
Title: Professor
Telephone: (919) 537-3217
Mailing Address:
UNC School of Dentistry
CB #7455
Chapel Hill, NC 27599-7455
Office: 4606 Koury Oral Health Sciences Bldg.
Lab: 4605 A-E Koury Oral Health Sciences Bldg.
Email: mitsuo_yamauchi@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Mitsuo+Yamauchi&u_id=5001330
Description of Research:
Biology and chemistry of extracellular matrix proteins, Biological significance of collagen post-translational modifications in mineralization, tissue stability, aging and cancer metastasis, Role of small leucine-rich proteoglycans in growth factor function and bone tissue engineering
Keywords: Aging, Biochemistry, Bone, Collagen, Dentin, Enzymes, Extracellular matrix molecules, Mineralization, osteoblasts, Tissue engineering, Collagen post-translational modification, osteogenesis imperfecta, cancer metastasis
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, postdoc and/or junior faculty member

 


 

ZajacName: David Zajac
Department: Dental Ecology
Title: Associate Professor
Telephone: (919) 537-3525
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 007 Brauer Hall
Lab: 016 Brauer Hall
Email: david_zajac@unc.edu
Lab URL: http://www.unc.edu/~dzajac
ReachNC Link: http://www.experts.scival.com/reachnc/expert.asp?n=David+J+Zajac
&u_id=5001251
Description of Research:
My primary research involves speech production and perception in infants and children with cleft palate. We recently reported that school- aged children with cleft palate who produce backed tongue-tip articulation errors have restricted anterior maxillary arch width that contributes to these errors. We are also studying oral-motor control during feeding and the development of stop consonant production (sounds such as /b/ and /p/) in infants with cleft palate before and after palate repair.
Keywords: Children, Cleft lip-palate, Infants, speech production, speech aerodynamics, speech acoustics, velopharyngeal function
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member

 


 

Zandona-190Name: Andrea Ferreira Zandona
Department: Operative Dentistry
Title: Associate Professor
Telephone: (919) 537-3525
Mailing Address:
UNC School of Dentistry
CB #7450
Chapel Hill, NC 27599-7450
Office: 436 Brauer Hall
Lab: 3405 Koury Bldg
Email: andrea_zandona@unc.edu
ReachNC Link:
http://www.experts.scival.com/reachnc/expert.asp?n=Andrea+Ferreira+Zandona&u_id=1980109130
Description Research:
Caries detection and assessment, caries prevention, caries management, caries risk assessment,  decision making in caries management, cariology education
Keywords: Caries, cariology, cariogenicity, education research, enamel, fluoride, microbiology, sealants, saliva, clinical trials, diagnosis, digital image analysis, lasers, learning, plaque, biofilm, preventive dentistry, remineralizaiton, biofil, Metabolomics, metabolites
Willingness and interest to mentor:
Undergraduate/college student, graduate student, undergraduate DDS or DH student, and junior faculty member